Kulephera kwa Vitamini B12 ndi chimodzi mwa zofooka zambiri za zakudya. Zimayambitsa zizindikiro zosiyanasiyana, monga kutopa, kukumbukira ndi kugwedeza manja ndi mapazi. Chifukwa cha zizindikiro zosiyanasiyana ndikuti vitamini B12 imakhala ndi mbali yaikulu pamagulu osiyanasiyana.
Vitamini B12 Zimatani?
Vitamini B12 ili ndi ntchito yofunikira popanga DNA, yomwe ili ndi chibadwa cha thupi.
DNA imayambitsa mapangidwe abwino a gawo lililonse la thupi.
Vitamini B12 imathandizanso kuchepetsa homocysteine, imodzi mwa mankhwala omwe thupi limapezeka. Ngati homocysteine siyiyendetsedwe bwino, imayambitsa kutupa ndi kuwonongeka kwa thupi.
Zizindikiro ndi Zotsatira za kuchepa kwa Vitamini B12
Matenda a magazi amachepetsedwa ndi maselo ofiira a m'magazi (RBCs). Chiwonetsero chachikulu cha chipatala cha B12 chosowa ndi matenda a kuchepa kwa magazi, omwe ndi mtundu wa kuchepa kwa magazi komwe nthawi zambiri kumatulutsa kutopa ndi tachycardia (kuthamanga kwa mtima mwamsanga), ndipo nthawi zina chimbudzi. Vitamini B12 ndi zakudya zomwe zimayenera kupanga maselo ofiira a maselo ofiira. Ma CD amapereka oksijeni yopanga mphamvu m'thupi kuti athetse zofunikira zonse za thupi.
Matenda a Megaloblastic angapezeke ndi kuyesa kwa magazi.
Mphuno ya m'mitsempha ndi mtundu wa vuto la mitsempha. Izi zikutanthauza kuti mitsempha yokha imatha kuwonongeka kapena kuti pali vuto la myelin.
Myelin ndi chophimba chophimba cha mitsempha yowopsa. Vitamini B12 ndizomwe zimagwirizana ndi myelin, ndipo chifukwa chake kuchepa kwa vitamini B12 kumalepheretsa myelin kupanga zofunikira.
Ndi kusowa kwa B12, kuwonongeka kwa mitsempha yowonjezera kuphatikizapo kuchepa kwa myelin kumapangitsa kuti thupi liziyenda bwino. Mitsempha ya mthupi imayendetsa kayendetsedwe ka thupi ndi kumva.
Zizindikiro za mliri wa m'mimba zimakhudza miyendo ndi manja, ndipo zimatha kuwonjezera mikono ndi miyendo. Zizindikiro zofala kwambiri ndizo:
- Kugwiritsa ntchito
- Numbness
- Kufooka
Dementia ndi matenda omwe amakhudzidwa ndi kukumbukira komanso kusintha khalidwe. Pali zifukwa zambiri zomwe zimayambitsa matenda a dementia, ndipo kusowa kwa vitamini B12 ndi chimodzi mwa zifukwa zomwe zadziwika posachedwapa. Kafukufuku wa sayansi akusonyeza kuti chiwopsezo cha ma dementia chokhudzana ndi kuchepa kwa vitamini B12 chikhoza kukhala chifukwa cha kuchuluka kwake kwa homocysteine.
Zizindikiro za dementia zikuphatikizapo:
- Kuiŵala
- Kusamvetsetsa
- Vuto kuthetsa mavuto
- Kulephera kulingalira
- Kutaya kwokhoza kudzisamalira nokha
- Kusasamala
- Hallucinations
Kusokonezeka maganizo ndiko kuwonetsetsa kwa vitamini B12, ndipo kungakhale ndi kuperewera kwa magazi kapena kuvutika maganizo.
Stroke ndi matenda omwe amadziwika ndi kusokonezeka kwa magazi kupita ku ubongo, zomwe zimapangitsa kuti thupi likhale lopweteka. Kulephera kwa Vitamini B12 kungapangitse chiopsezo pakati pa achinyamata omwe sangawonongeke. Kaya pali mgwirizano waukulu kapena ayi, ndipo chiopsezo chikhoza kukhala chifukwa cha kuchuluka kwa homocysteine.
Myelopathy amatanthauza matenda a msana. Kulephera kwa Vitamini B12 kumayambitsa mtundu wa matenda a msana wotchedwa subacute kuphatikizana kwa msana wamtsempha, umene umataya myelin m'madera ena a msana wamtsempha omwe amachititsa nthawi, kuchepa ndi kumva.
Zizindikiro za kuwonongeka kwa msana kwa msana kumaphatikizapo:
- Kufooka
- Kunjenjemera, kukulira
- Kuthamanga
- Kusamalitsa mavuto
Kutulutsa lilime kumayambanso chifukwa cha kuchepa kwa vitamini B12. Glossitis ndilo dzina lofotokozera lilime lopweteka, losazolowereka lomwe lingabwere chifukwa cha kusowa kwa zakudya.
Mavuto Okhudzana ndi Vitamini B12 Kulephera
Matenda a chithokomiro ndi Multiple Sclerosis (MS) zikhalidwe zonsezi zimakhulupirira kuti zimagwirizana ndi njira yokhayokha. Matenda amadzimadzi ndi omwe amachititsa thupi kudziukira palokha.
Kufooka kwapadera kwapadera ndi matenda omwe amayamba chifukwa cha 'kudzipweteka' m'dera la m'mimba lomwe limaphatikizapo kutengera kwa vitamini B12.
Kawirikawiri, anthu omwe ali ndi matenda a chithokomiro kapena MS ali ndi vuto loyambitsa matenda ndi vitamini B12.
Zimayambitsa Vuto la Vitamini B12
Kutsika kwa Zakudya Zochepa
Vuto lalikulu la vitamini B12 ndi kusowa kwa vitamini B12 mu zakudya. Vitamini B12 ndi mchere womwe umapezeka muzinthu zamtundu monga nyama, nkhuku, nsomba, mazira ndi mkaka. Choncho ziwopsezo ndizoopsa kwambiri za mavitamini B12 omwe ali ndi zakudya zochepa, monga anthu omwe sagwidwa ndi matendawa omwe sadya zakudya zokwanira za vitamini B12.
Zakudya zina zimalimbikitsidwa ndi vitamini B12, ndipo ngati mukufuna kutulutsa vitamini B12 kupyolera mu zakudya zamagulu, muyenera kuyesetsa kupeza zakudya zamtunduwu.
Kutsika Kwambiri
Vitamini B12 imadwalitsidwa ndi matumbo aang'ono, koma amafunika kuyambirira kukonza m'mimba poyamba. Choncho, zina zomwe zimakhudza m'mimba kapena m'mimba mwazing'ono zingathe kusokoneza mavitamini B12. Chinthu choyambirira ndi mapuloteni opangidwa m'mimba omwe amakhala ndi vitamini B12 asanaloŵe m'matumbo aang'ono.
Matenda osadziletsa, opaleshoni ya opaleshoni ndi kupweteka kwa m'mimba ndizochitika zonse zomwe zimalepheretsa kupanga ndi kugwiritsira ntchito chinthu chofunikira, moteronso vitamini B12 mu zakudya sizingayende mokwanira m'thupi, ndipo m'malo mwake zimachotsedwa pamtumbo zosuntha.
Kumwa mowa mopitirira muyeso kumayambitsa kusintha kwa m'mimba, kumayambitsanso kupanga chinthu choyambitsa, kuchititsa kuti B12 ipewe.
Matenda a m'mimba monga Crohn's and Celiac Disease akhoza kuteteza mavitamini B12 moyenera m'matumbo aang'ono, kuchititsa kusowa ngakhale ali ndi vitamini B12 okwanira.
Nthenda yotaya magazi ndi matenda omwe amatha kuchepetsa kapena kuthetsa chinthu chofunikira kwambiri, mapuloteni m'mimba omwe amamanga chakudya cha B12 kuti amve. Zimenezi zimayambitsa vuto la B12 kudzera mu malabsorption. Kutha kwa mtundu wa B12 sikungathe kuchitidwa ndi pakamwa B12 m'malo mwake, ndipo kumafuna chithandizo ndi vitamini B12 shots.
Zizindikiro za kuwonongeka kwa magazi m'thupi zimaphatikizapo:
- Kutopa
- Kutaya mphamvu
- Lightheadedness
- Kusokonezeka maganizo
- Mutu
- Kuthamanga kwa mtima mwamsanga
- Kulira mu makutu
Mankhwala angathe kusokoneza mavitamini B12. Mankhwala omwe amayamba kuchepetsa mavitamini B12 ndi awa:
Metformin: mankhwala omwe amachiza matenda a shuga
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Mankhwala ambiri ogwiritsidwa ntchito pochiza kupweteka kwa mtima
Mawu Ochokera
Ngati muli ndi vuto la vitamini B12, zotsatira zake zambiri zingasinthidwe, makamaka pamayambiriro oyambirira. Kawirikawiri, ngati vuto lanu la vitamini B12 limayambitsidwa chifukwa cha kusowa kwa zakudya, zakudya zowonjezera kapena zakudya zowonjezera zingathandize kusintha mavitamini B12 anu.
Ngati vutoli limakhala losawonongeka chifukwa cha vitamini B12, nthawi zambiri zimakhala zothandiza kuti vitamini B12 yowonjezerapo kudzera mu jekeseni mmalo mwa jekeseni, chifukwa izi zimalola kuti mchere ulowe m'thupi mwachindunji.
> Zotsatira:
> Cerit L, Duygu H, Gulsen K, Kemal H, Tosun O, Ozcem B, Cerit Z, Gunsel A, Kardiol Pol. Ubale pakati pa vitamini B12 ndi chiwerengero cha SYNTAX. 2017; 75 (1): 65-70.
> Luciana Hannibal, Vegard Lysne, Anne-Lise Bjørke-Monsen, Sidney Behringer, Sarah C. Grünert, Ute Spiekerkoetter, Donald W. Jacobsen, ndi Henk J. Blom, Biomarkers ndi Zolinga za Kuzindikira Vitamini B 12 Kutha, Front Mol Biosci. 2016; 3:27, do: 10.3389 / fmolb.2016.00027