Ngati mukufuna kupeza vitamini D zowonjezereka, mukhoza kuona njira ziwiri pa masamulo: D2 ndi D3. Izi ndi mitundu iwiri ya vitamini D. Ngati ndikanatenga vitamini D ndikuwonjezera, ndingadalire ku D3, koma zingapangitse kuti, D2 yakhala ikugwiritsidwa ntchito kwa zaka zambiri.
Vitamini D imagwira ntchito ngati hormoni kuti thupi lanu lidziwe ndikugwiritsa ntchito calcium ndi kuika kuchuluka kwa kashiamu m'magazi anu.
Ngati simukupeza vitamini D okwanira, mudzawonjezera chiopsezo cha matenda a osteoporosis kapena matenda ena omwe amachititsa kuti mafupa azifooka monga osteomalacia ndi osteopenia. Vitamini D ndiyenso ndiwothandiza kuti chitetezo cha mthupi chitetezeke komanso mitsempha yeniyeni ndi minofu ikugwira ntchito.
Vitamini D Wachilengedwe Kwambiri
Cholecalciferol (ndiyo D3) ndi mawonekedwe a vitamini D omwe amapezeka minyama. Pamene khungu lanu limadziwika ndi kuwala kwa dzuwa, Thupi lanu limatembenuza chinthu chotchedwa 7-Dehydrocholesterol kudzera m'magulu angapo a zamoyo kuti cholecalciferol. Ndiye kupyolera mu sitepe ina, cholecalciferol imasandulika kukhala calcifediol, yomwe imatchedwanso 25-hydroxyvitamin D3 ndipo ndiyo mawonekedwe omwe labotale imayendera pamene dokotala akulamula mayeso a vitamini D.
Pomaliza, thupi lanu limatembenukira ku calcifediol mu vitamini D (yomwe imagwira ntchito) yotchedwa calcitriol.
Zomera zimayenda mofanana, koma mmalo mwa cholecalciferol, zomera ndi ergocalciferol (D2).
Cholecalciferol ndi ergocalciferol ndizofanana kwambiri ndi zakumapeto kwa zaka za m'ma 1920, zinadziwika kuti ergocalciferol inali yopindulitsa pochizira ana. Kwa zaka zambiri, ergocalciferol yavomerezedwa ngati mavitamini D. owonjezera.
M'zaka za m'ma 1980 ndi 90s, asayansi ananena kuti mawonekedwe a nyama, D3, anali othandiza kwambiri kukulitsa mavitamini D3 (25-hydroxyvitamin D3).
Kuchokera apo, maphunziro ena awiri sanapeze kusiyana pakati pa mitundu iwiriyo ndipo gawo lachitatu linapeza kuwonjezeka kofulumira ndi D3 zowonjezereka, koma ochita kafukufuku sankawonekeratu ngati izo zinapanga kusiyana kwakukulu thrapeutically.
Chifukwa chiyani maphunzirowo ali ndi zotsatira zosiyana? Zambiri zingakhudze kafukufuku wa mtundu umenewu. Kafukufuku wina anachitidwa m'chilimwe kuti dzuwa lituluke likhoza kuwononga zotsatira zake. Ndipo mwinamwake zakudya ndi kugwiritsa ntchito zakudya zowonjezera zakudya zingasinthe zinthu. Ndiponso ndi ndani yemwe ali gulu labwino kwambiri la anthu oti aziphunzira? Odwala odwala matenda opatsirana? Matenda a impso? Anthu odwala, omwe angakhale ndi vitamin D ochepa chabe? Anthu achikulire? Achinyamata? Amuna? Akazi? Kafukufuku akhoza kukhala wovuta chifukwa zomwe apeza pa gulu limodzi la anthu ali ofanana ndi wina.
Ndikutsimikiza kuti kafukufuku adzachitidwa pa kusiyana pakati pa D2 ndi D3. Koma pakadali pano, ngati mukuda nkhawa ndi mavenda anu a vitamini D , chinthu chabwino kwambiri ndi kupita kwa wothandizira zaumoyo kuti mavitamini D awononge magazi anu. Ngati ali otsika, mungatenge mtundu uliwonse wa vitamini D ndipo patatha masabata angapo, yesani magazi anu kuti muwone ngati zowonjezerako zikugwira ntchito.
Nthawi zonse muzitsatira malangizo omwe mumalandira kuti mutenge vitamini D pokhapokha ngati wothandizira zaumoyo wanu akukuuzani mosiyana.
Zotsatira:
Armas LA, Hollis BW, Heaney RP. "Vitamini D2 ndi yopambana kwambiri kuposa vitamini D3 mwa anthu." J Clin Endocrinol Metab. 2004 Nov; 89 (11): 5387-91.
Glendenning P, Chew GT, Seymour HM, Gillett MJ, Goldswain PR, Inderjeeth CA, Vasikaran SD, Taranto M, Musk AA, Fraser WD. "Seramu 25-hydroxyvitamin D imakhala ndi mavitamini D-osakwanira kugwira ntchito kumapeto kwa odwala atatha kupatsirana ndi ergocalciferol ndi cholecalciferol." Thupi. 2009 Nov; 45 (5): 870-5.
Holick MF, Biancuzzo RM, Chen TC, Klein EK, Young A, Bibuld D, Reitz R, Salameh W, Ameri A, Tannenbaum AD. "Vitamini D2 imathandiza kwambiri monga vitamini D3 poyendetsa makina 25-hydroxyvitamin D." J Clin Endocrinol Metab. 2008 Mar; 93 (3): 677-81.
NIH Ofesi Zowonjezera Zakudya. "Chakudya Chakudya Chakudya: Vitamini D."