Zifukwa Zitatu Musadere Nkhawa za LDL Yanu
Ngakhale zizindikiro zambiri za thanzi nthawi zambiri zimawongolera pa zakudya zochepa ( carglycerides , HDL cholesterol, shuga wa magazi, kuthamanga kwa magazi, chiuno / chiuno, etc), zotsatira za katakiteriya odya pa LDL cholesterol amatha kusintha, anthu ali ndi kuchepa ndipo ena akuwonjezeka. Anthu ena amanjenjemera ngati akuwona kuchuluka kwa chiwerengerocho, pamene madokotala awo akuyesa mankhwalawa.
Koma pali zifukwa zosachepera zitatu zomwe zimapangitsa kuti mpweya usapite patsogolo.
Cholesterol N'chiyani?
Cholesterol ndi mankhwala okhudzana ndi mafuta. Ngakhale kuti chotupa cha LDL nthawi zambiri chimatchedwa "choipa", ndikuganiza ndikofunikira kumvetsa kuti cholesterol, mkati mwake, sichimakhala choipa - kwenikweni, ndizofunika kuti matupi athu athamange. Sitikukweza nkhaniyi kunena kuti tidzafa popanda cholesterol. Cholesterol ndi gawo la maselo athu omwe amachititsa kuti thupi lathu lisamachite mantha. Amagwiritsidwanso ntchito pakupanga mahomoni ambiri (monga estrogen ndi testosterone), vitamini D, zinthu zomwe zimakhala zofunika kuti chimbudzi, ndi zina zambiri. Thupi lathu limapanga cholesterol - malingana ndi zizoloŵezi zathu zakudya, paliponse kuyambira 80-100% ya cholesterol mu matupi athu amapangidwa "mkati".
Kodi LDL Cholesterol Ndi Chiyani Choipa Kwambiri?
Zimakonda kunena za "mitundu yambiri ya cholesterol", koma izi sizolondola.
Makululeti onse a cholesterol ali chimodzimodzi; Ndizowona kuti iwo ali ndi mauthenga osiyanasiyana kuti azitengedwera kudzera m'magazi athu. "Thupi loyendetsa" limatchedwa lipoprotein. HDL ndifupi ndi "high-density lipoprotein" ndipo nthawi zina imatchedwa "cholesterol wabwino". LDL ndifupi ndi "low-density lipoprotein" ndipo nthawi zambiri amatchedwa "cholesterol choipa".
(Pali gawo lachitatu, lotchedwa VLDL la "chochepa kwambiri" lipoprotein, lomwe lingatchedwe "cholesterol choipa", koma pali zambiri zochepa.) Ndi LDL yomwe imagwirizana kwambiri ndi matenda a mtima okhudzana ndi zipika mu mitsempha.
Koma dikirani, pali zambiri! Onse awiri a HDL ndi a LDL amapatulidwa kukhala mitundu yosiyanasiyana, ndipo zambiri zimapezeka za "magawo omwe ali mkati mwa magawo" a lipoproteins. Pankhani ya LDL, kusiyana kwakukulu kwa mitunduyi ndiko kukula ndi kuchuluka kwa maselo a LDL. Anthu ambiri awonetsa kuti chiwerengero cha LDL sichinali chokwanira kwambiri podziwa yemwe adzapitirire kudwala matenda a mtima, koma kupezeka kwa machitidwe a kukula kwa tinthu kwamupatsa madokotala zambiri zokhudza momwe LDL ya munthu ali. Koma zambiri za izi mu # 2 pansipa - choyamba ndikufuna kutchula mwachidule:
1. Kukula kwa LDL kawirikawiri Kumakhala Kochepa
Pakhala pali maphunziro angapo tsopano akutsata LDL pa zakudya zochepa. Zina mwa izo, pali chizoloŵezi cha anthu ena kukhala ndi LDL yokweza pamwezi wa 3-4, koma mwezi wa 6 kapena 8, iwo amatha kubwerera mmbuyo. Ndamva nkhani zambiri m'magulu otsika kwambiri. Kotero zikuwoneka kuti ndi kwanzeru kusunga dzanja lanu pazithunzi zoopsya mu miyezi yoyambirira ya pulogalamu yanu yochepa ya kudya carb.
(Chifukwa cha zochitika izi, monga momwe ndikudziwira, sichidziwika, koma zanenedwa kuti cholesterol chosungunuka m'maselo akulu akhoza kumasulidwa m'magazi a magazi panthawi ya kuchepa kwa thupi, ndipo zingakhale zofunikira makamaka miyezi ingapo yoyambirira pamene kulemera kwake kumathamanga kwambiri.)
2. Mitengo ya Kukula kwa Matenda Kawirikawiri Kumachepetsa pa Zakudya Zochepa za Carb
Ndiye bwanji timasamala za kukula kwa particles za LDL? Zimakhala kuti mukakhala ndi tizilombo tating'onoting'ono, tinthu tating'ono ta LDL (kutchedwa Chitsanzo B), ndizowonongeka kwambiri ndi matenda a mitsempha yapamwamba kuposa pamene particles ndi zazikulu komanso zochepa (Pattern A).
Mu phunziro lililonse ndikudziwa zomwe zimawoneka kukula kwa tinthu ta LDL pamene anthu amasinthasintha ku zakudya zapakitale, machitidwe adasinthidwa.
N'chifukwa chiyani zazikulu zazikuluzikuluzigawo zimakhala zotetezeka? Ndamva chithunzi chochititsa chidwi ndi wolemba Dr. Mark Houston (mvetserani kufunsa pano - kuyambira pa August 25, 2012, ponena za "Funsani Dr. Dawn"). Anafotokoza kuti m'malo moganiza kuti cholesterol imangokhala mkati mwa mitsempha, imayambira m'kati mwake pamphepete mwa epithelium (yomwe ili ngati "khungu" la mitsempha) pamene pali kuwonongeka ndi kutupa mu epithelium.
Cholesterol (kapena, molondola, lipoprotein) particles kuchokera m'magazi ndiye amalowetsa pansi pa epithelial wosanjikiza ndi kumanga kuchokera apo kuti apange chipikacho. Pamene ikukula, chikwangwani chimayamba kutseka mitsempha. Pofotokoza zotsatira za kukula kwa tinthu, Dr Houston anapereka fanizo ili: Tangoganizirani ukonde pa khoti la tenisi. Mpira wa tenisi sudzadutsa mumtsinjewo, koma ngati mutaponya gulu la galasi pa ukondewo, ena a iwo adzadutsa. Izi zimapangitsa kuganiza mozama za chifukwa chake tizilombo tating'onoting'ono ta LDL ndizoopsa kwambiri kusiyana ndi zazikulu, "fluffier" particles - ndizing'ono, zolemera kwambiri zomwe zimatha kukhala malo owonongeka. (Dr. Houston akunenanso kuti chiŵerengero cha LDL particles chingakhale chofunikira.)
Simudzapeza za LDL particles pamayeso a kolesterolini. Dokotala wanu ayenera kulamula mayeso apadera. Izi ndiziwirizi:
- Zojambulajambula Zowonongeka (VAP)
- Gel Electrophoresis Yamtengo Wapatali (GGE)
3. LDL Kawirikawiri Sichiyesedwa Mwachindunji, Chimene Chikhoza Kukhala Chovuta
Zimakhala zovuta kuyeza LDL molunjika, choncho mababu nthawi zambiri amagwiritsa ntchito ndondomeko kuti aziwerengera LDL kuzizira zina zamagazi. Amatchedwa Friedewald equation ndipo izi ndi izi: LDL = Total Cholesterol - HDL - (Triglycerides / 5). Kwa anthu ambiri, njirayi ndi yolondola kwambiri, ngakhale kuti chikhalidwe cha masamu chidzazindikira kuti njira imodzi yowonjezera "mpikisano wanu wa LDL ingakhale kukulitsa triglycerides yanu, mwachitsanzo, kudya msuzi wa shuga. (Osati lingaliro labwino !! Izi zimangotanthauza vuto lomwe lingakhalepo.) Tsopano, zimadziwika kuti triglycerides ndipamwamba kwambiri (kuposa 400 mg / dL) kuyanjana sikupereka zotsatira zolondola. Koma palinso kukudandaula kuti pamene triglycerides ali osadziwika bwino (pansi pa 100) LDL ikhoza kugwedezeka pogwiritsa ntchito njirayi. Pakhala pali maphunziro angapo pazinthu izi, komanso mauthenga ochokera kwa madokotala omwe amaletsa chilolezo m'magazi monga gawo la mankhwala awo okhuta kwambiri ndi shuga. Anthu omwe amadya zakudya zamagetsi omwe amatsatira zakudya nthawi zonse amapeza kuti triglycerides ikugwera pansi pa 100 (pafupifupi dokotala wina, Dr. Mary Vernon, amagwiritsa ntchito triglycerides ngati chimodzi mwa zizindikiro kuti amuuze ngati wodwala akutsatira chakudya ). Choncho ngati triglycerides ali otsika ndipo LDL ili pamwamba, zingakhale bwino kupempha mayesero omwe amayesa LDL molunjika mmalo mogwiritsa ntchito Friedewald.
Mmodzi mwa magulu amene adaphunzira izi (Ahmadi et al) adayambitsa njira yowonjezera, yomwe nthawi zambiri imatchedwa Iran equation. Ngakhale n'kofunika kuzindikira kuti mgwirizanowu siwolandiridwa mwapadera m'dera lachipatala ku United States, zingakhale zosangalatsa kufanizitsa LDL yanu-yotengedwa ndi migwirizano yosiyanasiyana.
Chochititsa chidwi, kukhala ndi triglycerides pansi pa 100 kumagwirizananso ndi Pattern A LDL tinthu kukula (njira ya thanzi). Choncho ngati mukutsatira chakudya chochepa kwambiri ndipo mumakhala otsika kwambiri, pali zifukwa ziwiri zoti musadere nkhawa kwambiri za LDL cholesterol, mpaka mutayesedwa.
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