Forskolin ndi mankhwala achibadwa akuti amapereka madalitso angapo a thanzi. Kuchokera ku chomera cha Coleus forskohlii , forskolin amadziwika kuti ayambitse adenylate cyclase (enzyme yomwe ikukhudzana ndi kuyang'anira ntchito zambiri zamagetsi).
Ntchito
Otsutsa akuti forskolin ikhoza kuthandizira kupewa kapena kusamalira zinthu zosiyanasiyana za thanzi, kuphatikizapo:
- Nthendayi
- Phumu
- Glaucoma
- Kuthamanga kwa magazi
Forskolin amanenedwa kuti amalimbikitsa kuchepa kwa thupi, kuteteza kansana, komanso kusintha thanzi la mtima.
Ubwino wa Zaumoyo
Mpaka pano, palibe chithandizo chochepa cha sayansi pazinthu zotsutsa za forskolin pa umoyo waumunthu. Pano pali kuyang'ana pazowunikira zingapo kuchokera ku kafukufuku wopezeka pa forskolin:
1) Kutaya Kwambiri
Forskolin ingathandize kuchepetsa kunenepa kwambiri, malinga ndi kafukufuku wochepa wofalitsidwa mu Obesity Research mu 2005. Phunzirolo, amuna 30 olemera kwambiri kapena olemera kwambiri anapatsidwa kuti alandire forskolin kapena placebo tsiku lililonse kwa milungu 12. Kumapeto kwa phunziroli, mamembala a gulu la forskolin amasonyeza kuchepa kwakukulu kwa mafuta a thupi ndi kuwonjezeka kwakukulu kwa thupi lofooka (poyerekezera ndi mamembala a gulu la placebo). Ophunzira omwe anachitidwa ndi forskolin adakumananso ndi kukula kwa fupa.
2) Madontho a Diso
Kafukufuku wakale wokhudza nyama akusonyeza kuti madontho a diso omwe ali ndi forskolin angathandize kuteteza glaucoma.
Mwachitsanzo, maphunziro awiri pa akalulu adapeza kuti forskolin ikhoza kuchepetsa kupanikizika kwa m'mimba (chinthu chofunika kwambiri pa chitukuko cha glaucoma).
3) Nsalu
Kafukufuku wamaphunziro pa zinyama amasonyeza kuti kugwiritsa ntchito forskolin khungu kungayambitse khungu. Mufukufuku wokhudzana ndi ndondomeko yomwe inafalitsidwa mu Nature mu 2006, mwachitsanzo, asayansi anawonetsa kuti forskolin ingathandize kuyendetsa khungu la khungu ndikupangira khungu popanda kuwala kwa ultraviolet.
Komabe, palibe umboni wakuti forskolin ikhoza kuyambitsa khungu kwa anthu.
4) Nthenda
Forskolin angakuthandizeni kupewa matenda a mphumu, kafukufuku wa 2006 wochokera ku Journal of International Medical Research akusonyeza. Kafukufukuyu anapeza kuti matenda a mphumu anali ochepa kwambiri pakati pa odwala omwe ankatenga forskolin capsules (poyerekeza ndi omwe adalandira chithandizo cha mankhwala a sodium cromoglycate, mankhwala opatsirana a mphumu). Phunziro lachisanu ndi chimodzi losatha, phunziroli linakhudza ana makumi anayi ndi akulu omwe ali ndi mphumu yosalekeza kapena yochepa.
Mipango
Forskolin ikhoza kuchititsa zotsatira zosiyanasiyana, kuphatikizapo mutu ndi hypotension (chikhalidwe chomwe chimayikidwa ndi kutsika kwa magazi pang'ono). Kuonjezera apo, forskolin iyenera kupeŵedwa ndi anthu omwe ali ndi matenda a impso a polycystic ndi anthu omwe amagwiritsa ntchito mankhwala ozunguza magazi komanso / kapena mankhwala ochepetsa magazi.
Kugwiritsa Ntchito Ito la Thanzi
Ngakhale kufufuza koyambirira kumasonyeza kuti forskolin ikhoza kupindulitsa, chifukwa cha kusowa kochita kafukufuku, ndiposachedwa kwambiri kuti mutsimikizire forskolin kuti ali ndi matenda aliwonse. Ngati mukuganiza kuti ntchito ya forskolin ikudwala chifukwa cha matenda aakulu, lankhulani ndi dokotala musanayambe kulembetsa mankhwala owonjezera. Kudziletsa nokha ndi kupewa kapena kuchepetsa kusamalidwa kosatha kungakhale ndi zotsatira zoopsa.
Zotsatira
D'Orazio JA, Nobuhisa T, Cui R, Arya M, Spry M, Wakamatsu K, Igras V, Kunisada T, Granter SR, Nishimura EK, Ito S, Fisher DE. "Njira yothandizira mankhwala osokoneza bongo komanso chitetezo cha khungu chochokera pa ntchito ya Mc1r mu kuwotcha kwa UV." Chilengedwe. 2006 Sep 21; 443 (7109): 340-4.
Godard MP, Johnson BA, Richmond SR. "Maonekedwe a thupi ndi mavitamini omwe amagwiritsidwa ntchito ndi forskolin akumwa kwambiri kuposa amuna." Obes Res. 2005 Aug; 13 (8): 1335-43.
González-Sánchez R, Trujillo X, Trujillo-Hernández B, Vásquez C, Huerta M, Elizalde A. "Forskolin motsutsana ndi sodium cromoglycate pofuna kupewa chifuwa cha mphumu: kuyesa kachipatala kamodzi kokha." J Int Med Res. 2006 Mar-Apr; 34 (2): 200-7.
Li X, Nie L, Yang W, Chen Z, Wang X, Luo L. "Kulepheretsa mphamvu ya isoforskolin ndi forskolin pa matenda a hypertension mu akalulu." Chinese Journal of Ophthalmology. 2000 Jul; 36 (4): 292-4.
Chikumbutso cha Memorial Sloan-Kettering Cancer Center. "Za Herbs: Forskolin". March 2011.
Zeng S, Shen B, Wen L, Hu B, Peng D, Chen X, Zhou W. "Kafukufuku wofufuza za zotsatira za Forskolin pochepetsa kupuma kwa m'mimba." Diso la Sayansi. 1995 Sep; 11 (3): 173-6.